This paper discusses the antiatherosclerotic effects of selected plant flavonoids such as quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin.Įxtração de ecdisterona em raÃzes de ginseng brasileiroįlores,Rejane Nicoloso,Fernando Teixeira Brondani,Daniela Maldaner,Joseila Cezarotto,Verciane Giacomelli,Sandro RogérioĮste estudo teve como objetivo otimizar a extração de ecdisterona em raÃzes de ginseng brasileiro. The future development of flavonoids-based drugs is believed to provide significant effects on atherosclerosis and its related diseases. The flavonoids compounds also exhibit lipid lowering effects and anti-inflammatory and antiatherogenic properties. Since the usage of the synthetic drug, statins, leads to various side effects, the plants flavonoids with antiartherosclerotic activity gained much attention and were proven to reduce the risk of atherosclerosis in vitro and in vivo based on different animal models. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. This extration method has been successfully applied for determination of ecdysterone content from roots of Brazilian ginseng, and could be useful for the quality control of drugs and pharmaceutical formulations.Īntiartherosclerotic Effects of Plant Flavonoidsįull Text Available Atherosclerosis is the process of hardening and narrowing the arteries. In both studied species, the highest ecdisterone content was detected from samples extracted in a Soxhlet and using methanol as a solvent. The ecdysterone content was determinated using high efficiency liquid chromatography methods. tuberosa, the roots samples were extracted with methanol in a Soxhlet or in ultrasonic. In the second trial, the extration was conduced in a Soxhlet or ultrasonic using metanol as a solvent. glomerata were extracted in a Soxhlet with methanol or chloroform for 4h. Root samples of two accessions (BRA and JB-UFSM of P. tuberosa, podendo ser aplicada no controle de qualidade de drogas vegetais e/ou fitoterápicos.This study aimed at optimizing the extraction method from ecdysterone of Brazilian ginseng. A metodologia proposta mostrou-se eficaz para a quantificação da ecdisterona a partir das raÃzes de P. Em ambas as espécies, um maior conteúdo de ecdisterona foi detectado nas amostras extraÃdas com metanol e em Soxhlet. O conteúdo de ecdisterona foi determinado em Cromatógrafo LÃquido de Alta Eficiência (CLAE. tuberosa, as amostras foram extraÃdas com metanol, e a extração foi conduzida em Soxhlet e em banho ultrasônico. No segundo ensaio, com o intuito de se escolher o método extrator, a extração foi conduzida em Soxhlet e em ultrassom, utilizando metanol como solvente. glomerata foram extraÃdas em Soxhlet com metanol e clorofórmio, separadamente, durante 4 horas. Primeiramente, para se avaliar a eficiência do solvente extrator, amostras de raÃzes dois acessos (BRA e JB-UFSM de P. Beside their function as pigments in flowers and fruits, to attract pollinators and seed dispersers, flavonoids are involved in UV-scavenging,Įxtração de ecdisterona em raÃzes de ginseng brasileiro Extraction of ecdysterone from roots of Brazilian ginsengĭirectory of Open Access Journals (Sweden)įull Text Available Este estudo teve como objetivo otimizar a extração de ecdisterona em raÃzes de ginseng brasileiro. In plants, flavonoids play an important role in biological processes. Bovy, A.G.įlavonoids comprise the most common group of polyphenolic plant secondary metabolites. ![]() Modification of flavonoid biosynthesis in crop plants
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